Ua atia'e e Saienitisi se fa'avae mo le fa'apipi'iina o vaega meafaitino fa'anosized, po'o "mea-nano," e matua'i 'ese'ese ituaiga - fa'aletino po'o fa'alenatura - i fausaga 3-D mana'omia.E ui lava o le faʻapipiʻiina o le tagata lava ia (SA) ua faʻaaogaina lelei e faʻatulaga ai nanomaterials o le tele o ituaiga, o le faagasologa ua matua faʻapitoa-faʻapitoa, faʻatupuina fausaga eseese e faʻavae i luga o mea totino o meafaitino.E pei ona lipotia mai i se pepa na lolomiina i aso nei i Nature Materials, o la latou DNA-programmable nanofabrication platform e mafai ona faʻaogaina e faʻapipiʻi ai le tele o mea 3-D i auala tutusa i le nanoscale (billionths o le mita), lea e tulaga ese ai mata, vailaʻau. , ma isi meatotino ua aliali mai.
"O se tasi o mafuaʻaga autu e le o se auala e filifili ai le SA mo faʻaoga faʻaoga e le mafai ona faʻaogaina le faiga tutusa o le SA i luga o le lautele o meafaitino e fatu ai faʻasologa tutusa 3-D mai nanocomponents eseese," o le faʻamatalaina lea e le tusitala o Oleg Gang. , taʻitaʻi o le Soft and Bio Nanomaterials Group i le Center for Functional Nanomaterials (CFN) - o le US Department of Energy (DOE) Office of Science User Facility i Brookhaven National Laboratory - ma se polofesa o le Inisinia Kemisi ma le Faʻaaogaina o le Physics and Materials Science. i Columbia Engineering."O iinei, matou te vavaeeseina le faagasologa o le SA mai meafaitino e ala i le mamanuina o polyhedral DNA faʻamalama e mafai ona faʻapipiʻiina ni mea faʻapitoa poʻo mea faʻapitoa, e aofia ai metala, semiconductor, ma e oʻo lava i polotini ma enzymes."
Sa fa'ainisinia e le au saienitisi fa'avaa DNA fa'atusa i foliga o se kupita, octahedron, ma le tetrahedron.I totonu o fa'ava'a o lo'o iai "lima" DNA e na'o mea nano-mea fa'atasi ma le fa'asologa o DNA e mafai ona fusia i ai.O nei mea voxels - o le tuʻufaʻatasia o le faʻavaa DNA ma le nano-mea - o poloka faufale ia e mafai ona faia ai le macroscale 3-D structures.O fa'avaa e feso'ota'i le tasi i le isi e tusa lava po'o le a le ituaiga nano-mea o lo'o i totonu (pe leai) e tusa ai ma fa'asologa fa'atasi o lo'o fa'apipi'iina i o latou pito.Fa'alagolago i o latou foliga, o fa'avaa e ese le aofa'i o vertices ma fa'atupu ai le fa'atupu ese'ese atoa.So'o se nano-meafaitino e fa'afeiloa'i i totonu o fa'avaa e ave i luga o lena fa'atulagaga fa'avaa ma'oti.
Ina ia faʻaalia la latou faʻapotopotoga, na filifilia e saienitisi nanoparticles (auro) ma semiconducting (cadmium selenide) ma se polotini siama (streptavidin) e avea ma mea faʻapitoa ma mea faʻaletino e tuʻu i totonu o le DNA.Muamua, na latou faʻamaonia le faʻamaoni o le DNA faʻavae ma le faʻavaeina o mea voxels e ala i ata faʻatasi ma microscopes electron i le CFN Electron Microscopy Facility ma le Van Andel Institute, o loʻo i ai se seti o meafaifaʻaili e faʻaogaina i le vevela o le cryogenic mo faʻataʻitaʻiga o meaola.Ona latou suʻesuʻeina lea o fausaga lattice 3-D i le Coherent Hard X-ray Scattering and Complex Materials Scattering beamlines o le National Synchrotron Light Source II (NSLS-II) - o le isi DOE Office of Science User Facility i Brookhaven Lab.Columbia Engineering Bykhovsky Polofesa o Chemical Engineering Sanat Kumar ma lana vaega na faia le faʻataʻitaʻiga faʻatusatusaga e faʻaalia ai o le faʻataʻitaʻiga o le lattice structures (faʻavae i luga o le x-ray faʻataʻapeʻapeina mamanu) o mea aupito sili ona mautu le thermodynamic e mafai ona fausia e le voxels.
"O nei mea voxels e mafai ai ona tatou amata faʻaaoga manatu e maua mai i atoms (ma mole) ma tioata latou te faia, ma faʻafeiloaʻi lenei malamalama tele ma faʻamaumauga i faiga e fiafia i ai i le nanoscale," o le tala lea a Kumar.
Na fa'aalia e tamaiti a'oga a Gang i Columbia pe fa'apefea ona fa'aogaina le fa'aputuga fa'apotopotoga e fa'atūina ai le fa'atulagaina o ituaiga mea eseese e lua e iai le vaila'au ma galuega fa'atino.I se tasi tulaga, na latou faʻapipiʻi faʻatasi ni enzymes se lua, fatuina 3-D arrays ma le maualuga o le faʻapipiʻiina.E ui ina sa tumau pea le le suia o vailaʻau, ae na faʻaalia le faʻateleina o le gaioiga o le enzymatic.O nei "nanoreactors" e mafai ona faʻaogaina e faʻaogaina ai gaioiga faʻasolosolo ma mafai ai ona faʻapipiʻiina mea faʻamalosi.Mo le fa'ata'ita'iga o mea mata'utia, na fa'afefiloi ai lanu 'ese'ese se lua o togitogi fa'atusa - tama'i nanocrystals o lo'o fa'aaogaina e fai ai fa'aaliga televise ma le maualuga o le lanu ma le susulu.O ata na pu'eina i se microscope fluorescence na fa'aalia ai o le lattice na faia na fa'atumauina le mama o lanu i lalo ifo o le fa'atapula'aina (umi o galu) o le malamalama;o lenei meatotino e mafai ona fa'ataga mo le fa'aleleia atili o fa'ai'uga i fa'aaliga eseese ma feso'ota'iga feso'ota'iga.
"E manaʻomia ona tatou toe mafaufau pe faʻapefea ona fausia mea ma pe faʻafefea ona faʻaogaina," o le tala lea a Gang.“Atonu e le manaʻomia le toe faʻaleleia o meafaitino;na'o le afifiina o mea o iai i ni auala fou e mafai ona fa'aleleia atili ai a latou meatotino.E ono mafai, o la tatou fa'avae e mafai ona avea ma tekonolosi 'i tua atu o le 3-D lomitusi gaosiga' e fa'atonutonu ai meafaitino i fua la'ititi ma fa'atasi ai ma le tele o meafaitino eseese ma fatuga fuafuaina.O le faʻaaogaina o le auala lava e tasi e fausia ai 3-D lattices mai mea manaʻomia nano-meafaitino eseese vasega, tuʻufaʻatasia mea e ono manatu e le fetaui, e mafai ona suia le nanomanufacturing.
Mea e saunia e le DOE/Brookhaven National Laboratory.Fa'aaliga: E mafai ona fa'asa'o mea mo le sitaili ma le umi.
Maua tala fa'asaienisi lata mai ile ScienceDaily's free email newsletters, fa'afouina i aso uma ma vaiaso.Po'o le va'ai i fa'afouga fa'afouga ta'i itula i lau faitau RSS:
Ta'u mai ou manatu i le ScienceDaily - matou te talia fa'amatalaga lelei ma le le lelei.E i ai ni fa'afitauli i le fa'aogaina o le saite?Fesili?
Taimi meli: Iul-04-2022